Biochemistry nervous system 2021 prep Olzhayeva RR.pdf

 Cns IS BUILT UP FROM 2×1010 neurons and 3 times more glial

cells

• The weigh of the human brain is about 2% of the total body

weight, but glucose utilization reaches 66%

• The O2

consumption is about 25% of the total

• The main energy source for the brain is ATP generated by

oxidative phosphorylation

• creatine phosphate is able to store energy

• The CNS is protected from general metabolites of the blood

plasma by the blood-brain-barrier

• Nervous tissue is rich in phospholipids, sphingolipids, which

play an important role in cell membrane functions and myelin

formation

• water content: Myelin 40%, white matter 70%, grey matter 80%