Biochemistry nervous system 2021 prep Olzhayeva RR.pdf

Cns IS BUILT UP FROM 2x1010 neurons and 3 times more glial cells • The weigh of the human brain is about 2% of the total body weight, but glucose utilization reaches 66% • The O2 consumption is about 25% of the total • The main energy source for the brain is ATP generated by oxidative phosphorylation • creatine phosphate is able to store energy • The CNS is protected from general metabolites of the blood plasma by the blood-brain-barrier • Nervous tissue is rich in phospholipids, sphingolipids, which play an important role in cell membrane functions and myelin formation • water content: Myelin 40%, white matter 70%, grey matter 80%